orthokeratinized odontogenic cyst

Orthokeratinized odontogenic cysts OOC are developmental odontog enic cysts characterised by an orthokeratinized strati fied squamous epithelial lining. It has been categorized as a subtype of odontogenic keratocyst OKC.


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The orthokeratinized odontogenic cyst OOC is a rare developmental odontogenic cyst that has been considered as a variant of the keratocystic odontogenic tumour KCOT until Wright 1981 defined it as a different entity.

. The orthokeratinized odontogenic cyst OOC 1 was first clearly identified as an orthokeratinzed variant of the odontogenic keratocyst by Wright in 1981 2 owing to its different histopathology and reduced likelihood to recur. The keratocystic odontogenic tumor which was previously referred to as odontogenic keratocyst must be differentiated from other odontogenic cysts because of its aggressive behavior. Orthokeratinized odontogenic cyst OOC is an odontogenic cyst was initially termed as the uncommon orthokeratinized type of odontogenic keratocyst by the World Health Organization.

Orthokeratinized Odontogenic Cyst OOC is a rare developmental odontogenic cyst which was considered in the past to be a variant of Odontogenic keratocyst OKC later renamed as keratocystic odontogenic tumor KCOT. Orthokeratinized odontogenic cysts are a rare type of odontogenic cyst which are identified by an orthokeratinized stratified squamous epithelium. Orthokeratinized odontogenic cyst OOC is a rare intraosseous cyst characterized by an orthokeratinized epithelial lining and minimal clinical aggressiveness 1.

The orthokeratinized odontogenic cyst OOC is a developmental odontogenic cyst relatively rare arising from the cell rests of the dental lamina3 It was first described by Schultz in 1927 as an orthokeratinized variant of the formerly called OKC today known as the KCOT4 In 1992 World Health Organization. Orthokeratinized odontogenic cyst OOC a newly designated entity of odontogenic cysts is an intraosseous jaw cyst that is entirely or predominantly lined by orthokeratinized squamous epithelium. Orthokeratinized odontogenic cyst OOC is a developmental cyst of odontogenic origin and was initially defined as the uncommon orthokeratinized variant of.

Orthokeratinized odontogenic cyst OOC is a relatively uncommon developmental cyst comprising about 10 of cases that had been previously coded as odontogenic keratocysts OKCs. Only those reports of OOCs that occurred. Keratocystic odontogenic tumors can be seen at any age but are most common between 10 and 40 years of age in males and within the posterior mandible.

It usually occurs in mandible. Orthokeratinized odontogenic cyst OOC is an uncommon odontogenic cyst. Odontogenic cyst are a group of jaw cysts that are formed from tissues involved in odontogenesis tooth development.

Inflammatory such as periapical radicular cyst. Heterogenous group of lesions classified into three groups. The treatment of OOC is by enucleation and the prognosis following enucleation is excellent with a recurrence rate of less than 2.

The orthokeratinized odontogenic cyst may share some histologic features with OKC but is orthokeratinized not parakeratinized and lacks the palisaded basal cell layer. Cyst has orthokeratinized stratified squamous epithelial lining Cyst wall is fibrous and uninflamed Terminology Previously called orthokeratinized variant of odontogenic keratocyst OKC no longer recommended to use by WHO Epidemiology Comprised 105 of cases in series of odontogenic keratocysts Arch Pathol Lab Med 2010134271. In 2005 it was classified as a distinct entity.

Orthokeratinized Odontogenic Cyst OOC is a lesion characterized histologically by the presence of orthokeratinized cystic epithelium believed to be a distinct clinical entity from the widely known odontogenic keratocyst Odontogenic Keratocystic Tumor -OKT. Surgery is the usual treatment and recurrence or association with Gorlin-Goltz syndrome has rarely been described. A calcified odontogenic cyst has basal palisading but has very distinctive ghost cells.

Although both the first two editions of the World Health Organizations WHO histological classification of odontogenic tumours. The aims of the review were to evaluate the principal clinical and conventional radiographic features of orthokeratinized odontogenic cyst OOC by systematic review SR and to compare the frequency of OOC between four global groups. However they have been redefined as a distinct entity.

The orthokeratinized odontogenic cyst OOC is a rare developmental jaw cyst. Odontogenic cysts are closed sacs and have a distinct membrane derived from rests of odontogenic epitheliumIt may contain air fluids or semi-solid materialIntra-bony cysts are most common in the jaws because the mandible and maxilla are. Orthokeratinized Odontogenic Cyst OOC is a rare developmental odontogenic cyst which was considered in the past to be a variant of Odontogenic keratocyst OKC later renamed as keratocystic odontogenic tumor KCOT.

OOC should be histopathologically differentiated from OKC which has a higher recurrence rate and lower malignant potential. The orthokeratinized odontogenic cyst was recognized as a variant of OKC based on the presence of abundant orthokeratin in the cystic lining. The aim of this study was to report a large series of OOC to substantiate its clinicopathologic profiles and to investigate PTCH1 mutations in OOCs.

In 1981 Wright identified it owing to its different histology and relatively low recurrence rate as Orthokeratinized variant of odontogenic keratocyst OKC. 16 In 1981 Wright 2 reported 59 cases of what he then termed orthokeratinized variant of OKC which showed little clinical aggressiveness. Also heterogenous group of lesions such as nasopalatine duct cyst.

These cysts were originally classified as a subtype of odontogenic keratocysts. The suggestive etiology for OKC is either from epithelial remnants of tooth germ in the mandible and maxilla or the basal cell layer of the overlying surface epithelium. Orthokeratinized Odontogenic Cyst OOC is a rare developmental odontogenic cyst which was considered in the past to be a variant of keratocystic odontogenic tumor KCOT.

OOCs were first described in 1927 by Schultz 2 as a variant of odontogenic keratocysts now known as keratocystic odontogenic tumours KCOTs 3. Neoplastic such as keratocystic odontogenic tumor. They were originally believ ed to.

The databases searched were the PubMed interface of MEDLINE and LILACS. Developmental such as lateral periodontal cyst.


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